Publications

Long non-coding RNAs acting as mediators

Congratulations to Merve Keles obtaining his PhD with the thesis “Secreted long non-coding RNAs Gadlor1 and Gadlor2 act as mediators of cardiac remodelling during pressure overload”, where TATAA’s RNA spikes were successfully used as exogeneous controls.

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mRNA capping
Publications

Deciphering oligodendrocyte heterogeneity

Oligodendrocytes (OL) have been for decades considered a passive, homogenous population of cells that provide support to neurons, and show a limited response to pathological stimuli. This view has been dramatically changed.

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Publications

The MIQE Guidelines

MIQE Guidelines The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments Abstract (from Clinical Chemistry) Background: Currently, a lack of consensus exists on how best to

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molecular services to developers of cell and gene therapies
Publications

Respiration-Deficient Cancer Cells Growth

Cancer cells without mitochondrial DNA (mtDNA) do not form tumors unless they reconstitute oxidative phosphorylation (OXPHOS) by mitochondria acquired from host stroma. To understand why functional respiration is crucial for tumorigenesis, we used time-resolved analysis of tumor formation by mtDNA-depleted cells and genetic manipulations of OXPHOS.

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