DNA-seq

DNA Sequencing

Our DNA sequencing solutions provide comprehensive genetic analysis options for various sample inputs and methods to suit your needs.

Reveal genetic variations, discover drug targets, understand disease mechanisms, stratify patients, identify predictive or prognostic biomarkers, and explore other applications
genomic services

DNA-seq solutions

We support drug development from early discovery through clinical trials with tailored sequencing solutions customized to the biological sample, project goals, and regulatory requirements. Our services encompass everything from sample collection guidance to advanced bioinformatics analysis.

Integation Site Analysis TATAA Biocenter
Whole Genome Sequencing (WGS)

Whole genome sequencing provide a comprehensive view of all genetic variants, including single nucleotide variants (SNVs), insertions and deletions (indels), copy number variations (CNVs), and structural variants (SVs).

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Whole Exome Sequencing (WES)

Whole exome sequencing focuses on the protein-coding regions of the genome (the exome), which make up only 1-2% of the genome but harbor approximately 85% of known disease-related variants.

Targeted Gene Panels

Targeted sequencing panels covers specific genes or regions associated with particular diseases or drug responses. This highly focused approach is ideal for clinical trials, where specific genetic variants are of primary interest, providing efficient and relevant insights.

PK/PD​ TATAA Biocenter
Circulating Tumor DNA (ctDNA)

A non-invasive method that analyzes DNA fragments shed by tumors into the bloodstream. Liquid biopsy sequencing can be performed using WGS, WES, or targeted gene panels.

TCR-BCR seq
TCR/BCR-Seq

Study the diversity of T-cell and B-cell populations, revealing how specific clones expand or contract in response therapies or disease on RNA or DNA level.

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Services

Solutions for complex biological challenges

We offer a broad range of tailored commissioned services for drug development programs. With over two decades of expertise in nucleic acid analysis and sample preparation, we optimize workflows by assessing sample quality, validating performance, and analyzing clinical biomarkers using leading, well-matched technologies.

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Automated workflows

Enhance precision and productivity with automation

Most pipetting steps can be fully automated with our advanced liquid handling platforms.

Automation standardizes processes, ensuring consistent and precise results across experiments. By automating repetitive tasks such as sample handling and assay preparation, we can manage a higher volume of samples, accelerate project timelines, and easily scale to accommodate studies ranging from preclinical to large clinical cohorts. Our automated systems are fully integrated with our LIMS, ensuring accurate sample tracking, data traceability, and regulatory compliance.

Extraction

Accurate quantification begins with precise extraction

Comprehensive extraction across all sample types and test items

We have extensive experience extracting nucleic acids from various biological samples, including tissues, biofluids, swabs, excreta, secreta, fresh frozen, or FFPE-fixed.

Our expertise covers the extraction of different types of nucleic acids, including DNA, cfDNA, short RNAs (miRNA, siRNA, and more), messenger RNA, and ASOs with diverse modifications and chemical properties.

We consistently include spike-ins to ensure efficient extraction, optimal quality for downstream applications, and the removal of inhibitory agents. Our goal is the accurate quantification of the target molecule, where precise, high-quality extraction is essential for achieving both accuracy and precision.

About us

The power of our approach

Committed to quality, innovation, and fostering strong client relationships, we serve as your trusted partner to accelerate drug development. As a contract research organization, our mission is to push the boundaries of science and technology to generate accurate and reproducible data that shortens time-to-market.

Regulated laboratory environment

We are GLP accredited for qPCR, dPCR, and molecular biology, GCLP compliant, and ISO/IEC 17025 accredited. Our facility features a strict sample management process, a fully integrated LIMS system, backup for all vital systems, temperature and humidity control, and robust IT security.

Purpose-built PCR laboratory

Our purpose-built laboratory in Gothenburg, Sweden, is specifically designed for PCR. It has controlled air pressure, temporal separation, and biosafety cabinets to minimize contamination risk. This setup enables us to achieve the highest sensitivity and robustness required for validated assays. The lab is equipped with market-leading PCR and NGS instruments and advanced liquid handling systems.

Pioneers in assay development and validation

We are a team of 45 employees, with scientists at the forefront of assay development, optimization, and validation. Our team has co-authored key publications in the field, including Recommendations for Method Development and Validation of qPCR and dPCR Assays in Support of Cell and Gene Therapy Drug Development (AAPS J. 2024) and The MIQE Guidelines for qPCR and dPCR.

Flexible, client-centered solutions

We work closely with our clients to find tailored solutions, offering flexibility in sample types, test items, sample volume, and scalability. We prioritize transparency and proactive communication throughout each project, ensuring our clients are continuously updated on the progress.

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Let's explore how we can support your drug development program.

PK/PD​ bioanalysis

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