Early access service provider

Illumina Protein Prep (IPP) Solution

Illumina, the leader in NGS, is advancing into proteomics through a partnership with Standard BioTools (formerly SomaLogic). We are one of the few service centers worldwide equipped with the modified Tecan robot for the fully automated Illumina Protein Prep (IPP) workflow and the NovaSeq 6000. Be among the first to try it out!

Maximize discovery power

The Illumina Protein Prep (IPP) solution utilizes next-generation sequencing technologies’ renowned sensitivity, precision, and scalability, extending these capabilities to proteomics. This scalable, automated workflow is designed to bring the powerful exploratory potential of genomics and transcriptomics to protein analysis.
The readout is performed on a NovaSeq 6000, one of Illumina’s most advanced high-throughput sequencing platforms delivering massive, high-speed sequencing capacity.

Proteomics assay

The early access kit includes 6,000 unique human protein targets, analyzed using SOMAmer™ technology combined with Illumina’s NGS library conversion technology for precise and comprehensive protein profiling.

Automation

We are equipped with a Tecan Fluent 780, a high-performance automated liquid handling platform modified by Illumina specifically for the Illumina Protein Prep workflow.

Sequencing

At TATAA Biocenter, we utilize a NovaSeq 6000, one of the high-throughput sequencing platforms essential for the Illumina Protein Prep workflow. Each run analyzes 170 samples along with 22 controls.

Data analysis

Using cloud-based Illumina Connected Analytics, we manage and analyze large-scale data to provide normalized protein abundance. The Illumina Protein Prep workflow also supports tertiary analysis, enabling multiomic integration with transcriptomic data.

How IPP works

Target proteins are captured on magnetic beads using SOMAmer™ reagents.
Biotinylation
The proteins bound to the beads are then biotinylated.
IPP
UV light breaks the linker, releasing the now biotinylated proteins bound to SOMAmer™ reagents from the beads.
IPP
The released proteins are captured using streptavidin beads, which bind to the biotin.
IPP
The SOMAmers are eluted, barcoded, and sequenced. The quantification of SOMAmers serves as a proxy for the protein concentration in the sample.
About us

The power of our approach

Committed to quality, innovation, and fostering strong client relationships, we serve as your trusted partner to accelerate drug development. As a contract research organization, our mission is to push the boundaries of science and technology to generate accurate and reproducible data that shortens time-to-market.

Regulated laboratory environment

We are GLP accredited for qPCR, dPCR, and molecular biology, GCLP compliant, and ISO/IEC 17025 accredited. Our facility features a strict sample management process, a fully integrated LIMS system, backup for all vital systems, temperature and humidity control, and robust IT security.

Purpose-built PCR laboratory

Our purpose-built laboratory in Gothenburg, Sweden, is specifically designed for PCR. It has controlled air pressure, temporal separation, and biosafety cabinets to minimize contamination risk. This setup enables us to achieve the highest sensitivity and robustness required for validated assays. The lab is equipped with market-leading PCR and NGS instruments and advanced liquid handling systems.

Pioneers in assay development and validation

We are a team of 45 employees, with scientists at the forefront of assay development, optimization, and validation. Our team has co-authored key publications in the field, including Recommendations for Method Development and Validation of qPCR and dPCR Assays in Support of Cell and Gene Therapy Drug Development (AAPS J. 2024) and The MIQE Guidelines for qPCR and dPCR.

Flexible, client-centered solutions

We work closely with our clients to find tailored solutions, offering flexibility in sample types, test items, sample volume, and scalability. We prioritize transparency and proactive communication throughout each project, ensuring our clients are continuously updated on the progress.

contact us

Let's explore how we can support your drug development program

PK/PD​ bioanalysis

One form for all pages, including link to mailchimp.

"*" indicates required fields

×

Olink

"*" indicates required fields

What platform of interest?*
Name*

General Enquiries

Please fill in the form below and we’ll get back to you ASAP.

"*" indicates required fields

Name*

Courses

Please fill in the form for any courses request

"*" indicates required fields

Name*

Sign up to our Newsletter

"*" indicates required fields

Name*

Bioanalytical Services

Please fill in the form below and one of our bioanalytical experts will get back to you ASAP.

"*" indicates required fields

What services are you interested in?*
This field is hidden when viewing the form

Products

Please fill in the form below for any products request

"*" indicates required fields