Bioanalytical CRO
Sequencing for immunology and inflammatory disease drug development
We provide advanced sequencing technologies to help understand the molecular landscape in immunology and inflammatory disease drug development.
Neurodrug sequencing
Immune repertoire sequencing (TCR/BCR)
We use next-generation sequencing (NGS) to analyze T-cell receptor (TCR) and B-cell receptor (BCR) repertoires, providing valuable insights into the diversity and clonal expansion of immune cells in autoimmune diseases or in response to immunotherapy.
Regulatory compliance
We are GLP-accredited for preclinical qPCR and dPCR analyses, GCLP-compliant for clinical studies, and ISO/IEC 17025 certified to support regulatory submissions.
Pathway analysis
We examine inflammation signaling pathways and perform gene expression profiling using highly sensitive and specific targeted PCR assays, RNA sequencing, or protein profiling with Olink’s cytokine, chemokine, and immunology panels.
Project scalability
We offer comprehensive analysis services, from early-stage discovery to large-scale clinical trial sample testing, all in accordance with GCLP standards. Our capabilities include advanced robotics and sequencing instruments, allowing us to handle everything from small, manual sample series to high-throughput sequencing.
Services
Solutions for complex biological challenges
We standardize your custom workflow with a tailed method development. Our approach combines automated, predefined workflows with customized steps, ranging from sample transfer, homogenization, and extraction to downstream applications like NGS library preparation, dilutions, PCR mix preparation, and data interpretation.
technologies
We operate with the latest technologies
TATAA Biocenter comprises highly skilled scientists with extensive expertise in method development, data analysis, and optimization across diverse technologies. We leverage top-notch instrumentation and automated platforms, offering expert guidance to choose the most suitable technology on the market for your program.
PCR
We use highly sensitive and highly precise quantitative PCR (qPCR) and digital PCR (dPCR) technologies to detect one or multiple DNA/RNA targets in complex samples.
NGS
We use automated, customized workflows tailored to the sample type to simultaneously analyze thousands of genes, whole genomes, and either targeted RNA or full transcriptomes for both small and large-scale studies.
Quantitative proteomics
Olink’s proximity extension assays (PEA) allow multiplexed analysis of hundreds to thousands of proteins using just microliters of blood or plasma, ideal for immune studies and biomarker discovery or validation.
method validation
Accelerate drug development with validated assays
Validated bioanalysis is essential throughout the entire drug development process.
Assay validation ensures consistent and reliable performance, even with expected variations in conditions. We thoroughly validate each matrix, test item, and PCR assay, ensuring the workflow meets the required criteria, from extraction to sample analysis. The validation level is tailored to the specific context of use.
A validated assay is a valuable asset.
contact us
Let's explore how we can support your drug development program
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