Plasma proteomics
Bioanalytical CRO

Affinity-based proteomics

Analyzing plasma or serum for protein biomarkers provides critical insights into disease mechanisms, supports the development of targeted therapies, and allows for the evaluation of therapeutic responses, including target engagement, off-target effects, and immune responses.

Olink® and Illumina® Protein Prep Solution

Push the limits of plasma proteomics

Plasma and serum require complex depletion procedures for mass spectrometry to analyze proteins present at levels below the abundant albumin. Affinity-based proteomics, using antibodies or DNA aptamers to detect proteins, provides a powerful tool to explore a broader concentration range, process hundreds of samples simultaneously, and increase exploratory depth. As an early access partner with Illumina, we are one of the few centers offering both the Olink platform and the Illumina Protein Prep (IPP) Solution, enabling cross-validation studies and providing even broader protein coverage.

Plasma proteomics
Olink Service provider

Olink® Proximity Extension Assays

We are a certified Olink® service provider, offering Olink’s technology, which uses pairs of antibodies labeled with oligonucleotide barcodes to ensure high specificity in protein detection. Depending on the panel, the readout is performed using either qPCR or NGS. These panels cover a wide range of major pathways, conditions, and discovery areas, analyzing over 5,400 proteins in just microliters of serum or plasma.

Illumina logo

Illumina® Protein Prep (IPP) Solution

Illumina is a leader in the next-generation sequencing market for diverse DNA and RNA applications. Combining NGS technology with SOMAmer® DNA aptamers, which bind with high affinity to specific proteins, the new Illumina Protein Prep solution provides an automated workflow on a modified Tecan robot. This new solution enables the quantification of 6,000 unique human protein targets per sample on the Illumina NovaSeq 6000 instrument.

Services

Solutions for complex biological challenges

We offer a broad range of tailored commissioned services for drug development programs. With over two decades of expertise in nucleic acid analysis and sample preparation, we optimize workflows by assessing sample quality, validating performance, and analyzing clinical biomarkers using leading, well-matched technologies.

About us

The power of our approach

Committed to quality, innovation, and fostering strong client relationships, we serve as your trusted partner to accelerate drug development. As a contract research organization, our mission is to push the boundaries of science and technology to generate accurate and reproducible data that shortens time-to-market.

Regulated laboratory environment

We are GLP accredited for qPCR, dPCR, and molecular biology, GCLP compliant, and ISO/IEC 17025 accredited. Our facility features a strict sample management process, a fully integrated LIMS system, backup for all vital systems, temperature and humidity control, and robust IT security.

Purpose-built PCR laboratory

Our purpose-built laboratory in Gothenburg, Sweden, is specifically designed for PCR. It has controlled air pressure, temporal separation, and biosafety cabinets to minimize contamination risk. This setup enables us to achieve the highest sensitivity and robustness required for validated assays. The lab is equipped with market-leading PCR and NGS instruments and advanced liquid handling systems.

Pioneers in assay development and validation

We are a team of 45 employees, with scientists at the forefront of assay development, optimization, and validation. Our team has co-authored key publications in the field, including Recommendations for Method Development and Validation of qPCR and dPCR Assays in Support of Cell and Gene Therapy Drug Development (AAPS J. 2024) and The MIQE Guidelines for qPCR and dPCR.

Flexible, client-centered solutions

We work closely with our clients to find tailored solutions, offering flexibility in sample types, test items, sample volume, and scalability. We prioritize transparency and proactive communication throughout each project, ensuring our clients are continuously updated on the progress.

contact us

Let's explore how we can support your drug development program

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