Vector copy number assessments in CAR-T drug development

qPCR and dPCR are essential for vector copy number (VCN) quantification in CAR-T therapy, offering high sensitivity, specificity, and adaptability. Custom assay development, with proper validation, for each CAR construct ensures accurate results, supports regulatory compliance, and provides vital insights into CAR-T cell persistence and pharmacokinetics for effective and safe dosage and patient monitoring.