
Bioanalytical CRO
Immunoprofiling and immune response monitoring
We provide advanced immunoprofiling and immune response monitoring services to support the development of immunotherapies, cell and gene therapies, vaccines, and other biologics. Using state-of-the-art technologies, including TCR/BCR sequencing, qPCR/dPCR, NGS, and Olink proteomics, we deliver in-depth insights into the immune system’s behavior, helping you evaluate safety, efficacy, and immunogenicity throughout your drug development process.
Nucleic acid experts
Our technologies
We optimize and validate the entire workflow, from raw tissue specimens to the final data, ensuring the highest quality results are delivered.
TCR/BCR Sequencing (NGS)
Through comprehensive immune repertoire profiling, we provide detailed insights into the diversity and clonality of immune cells in immuno-oncology and vaccines. We run deep sequencing for high-resolution analysis of immune repertoires, allowing for the detection of rare immune clones and detailed characterization of immune responses.
qPCR/dPCR for cytokine and gene expression profiling
We develop and validate assays for targeted immune gene expression to precisely quantify cytokine, chemokine, and other immune-related gene expression. These assays support immunogenicity testing in biologics and vaccines, cytokine storm monitoring in CAR-T therapies and immunotherapies, and monitoring immune-related changes for safety and efficacy assessments.
Olink proteomics for immune biomarker analysis
Using Olink’s proximity extension assays (PEA), we provide multiplexed analysis of hundreds of immune biomarkers, including cytokines, chemokines, and inflammatory proteins, from small sample volumes for high-throughput protein biomarker profiling. Pre-made panels for multiplex cytokine and chemokine profiling and inflammatory markers are available to monitor multiple immune pathways simultaneously.
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applications
Support at every phase for well-informed decisions
Our molecular analyses support every phase of drug development, from early discovery through biomarker validation to large clinical cohort studies for efficacy and safety. We ensure precise, actionable insights at each stage, enabling informed decisions throughout the development.
Biomarker discovery and validation
Our biomarker discovery and validation services are designed to help you identify and validate biomarkers that predict drug response, efficacy, and safety. We offer comprehensive analysis support, from initial discovery using NGS and qPCR to multiplex protein biomarker validation.
Gene expression analysis
Cell and gene bioanalysis
We develop and validate highly sensitive assays from complex samples and unique test items through to final data for biodistribution, shedding, PK/PD, and transgene expression. Depending on regulatory requirements, the analysis is performed as fit-for-purpose, GLP, or GCLP.
Small non-coding RNAs
We use Two-tailed PCR technology to analyze short targets such as miRNA and siRNA. This technology enables high-throughput, validated qPCR/dPCR analyses for bioanalysis or biomarker purposes of these short targets.
Quantitative proteomics
Olink’s proximity extension assays (PEA) enable multiplexed analysis of hundreds to thousands of proteins using just microliters of blood or plasma, ideal for immune applications, biomarker discovery, or biomarker validation.
Genomic profiling and mutation detection
Our genomic profiling and mutation detection services identify key mutations for personalized therapies. We perform whole genome sequencing (WGS), exome sequencing, and targeted gene panels to deliver insights into SNPs, indels, CNVs, and structural variants.
About us
The power of our approach
Committed to quality, innovation, and fostering strong client relationships, we serve as your trusted partner to accelerate drug development. As a contract research organization, our mission is to push the boundaries of science and technology to generate accurate and reproducible data that shortens time-to-market.
Regulated laboratory environment
We are GLP accredited for qPCR, dPCR, and molecular biology, GCLP compliant, and ISO/IEC 17025 accredited. Our facility features a strict sample management process, a fully integrated LIMS system, backup for all vital systems, temperature and humidity control, and robust IT security.
Purpose-built PCR laboratory
Our purpose-built laboratory in Gothenburg, Sweden, is specifically designed for PCR. It has controlled air pressure, temporal separation, and biosafety cabinets to minimize contamination risk. This setup enables us to achieve the highest sensitivity and robustness required for validated assays. The lab is equipped with market-leading PCR and NGS instruments and advanced liquid handling systems.
Pioneers in assay development and validation
We are a team of 45 employees, with scientists at the forefront of assay development, optimization, and validation. Our team has co-authored key publications in the field, including Recommendations for Method Development and Validation of qPCR and dPCR Assays in Support of Cell and Gene Therapy Drug Development (AAPS J. 2024) and The MIQE Guidelines for qPCR and dPCR.
Flexible, client-centered solutions
We work closely with our clients to find tailored solutions, offering flexibility in sample types, test items, sample volume, and scalability. We prioritize transparency and proactive communication throughout each project, ensuring our clients are continuously updated on the progress.
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Let's explore how we can support your drug development program
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